Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528477 | 0.83 | FABP4 (0.44) | FABP4ALDH1A1FABP5KDM4EMAPK1 | |
| SCHEMBL14528727 | 0.79 | FABP4 (0.65) | FABP4ALDH1A1SMN1; SMN2FABP5KDM4E | |
| SCHEMBL14528595 | 0.77 | FABP4 (0.50) | FABP4ALDH1A1SMN1; SMN2FABP5KDM4E | |
| SCHEMBL14528482 | 0.73 | FABP4 (1.00) | FABP4ALDH1A1SMN1; SMN2FABP5KDM4E | |
| SCHEMBL24427083 | 0.71 | ALDH1A1 (0.47) | FABP4ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5197690 | 0.71 | MAPK14 (0.44) | FABP4FABP5NPSR1MEN1KMT2A | |
| SCHEMBL13587979 | 0.69 | MEN1 (0.47) | FABP4ALDH1A1SMN1; SMN2FABP5KDM4E | |
| SCHEMBL27207663 | 0.69 | MEN1 (0.45) | FABP4ALDH1A1FABP5KDM4EMEN1 | |
| SCHEMBL8235488 | 0.68 | KDM4E (0.50) | ALDH1A1SMN1; SMN2KDM4EMAPTTDP1 | |
| SCHEMBL26996417 | 0.68 | CTSD (0.44) | FABP4ALDH1A1SMN1; SMN2FABP5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181014-B1 | HETEROCYCLIC CONTAINING BIPHENYL aP2 INHIBITORS AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2007-05-23 | — | — | EP | disclosed |