Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885375 | 0.91 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL31613986 | 0.80 | RAB9A (0.69) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL1937499 | 0.80 | RAB9A (0.69) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL2435278 | 0.78 | MAPT (0.55) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL11618318 | 0.74 | RAB9A (0.85) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL5191043 | 0.74 | MAOB (0.68) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL3884307 | 0.73 | SMN1; SMN2 (0.56) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL1034943 | 0.73 | CA12 (0.72) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL29673209 | 0.73 | CA12 (0.72) | KDM4EALDH1A1HPGDHSD17B10CASP1 | |
| SCHEMBL3880364 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | RXFP1, RXFP2, CX3CR1 | KDM4E 4545/4885ALDH1A1 91/4885HPGD 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.