Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20210155 | 0.87 | MEN1 (0.38) | MEN1KMT2AMITFHRH4 | |
| SCHEMBL23641956 | 0.87 | MEN1 (0.38) | MEN1KMT2AMITFHRH4 | |
| SCHEMBL9698093 | 0.87 | MEN1 (0.38) | MEN1KMT2AMITFHRH4 | |
| SCHEMBL17918950 | 0.76 | KAT2B (0.36) | — | |
| SCHEMBL9699372 | 0.76 | GNAI3 (0.41) | MEN1KMT2AMITFHRH4 | |
| SCHEMBL4623536 | 0.75 | MEN1 (0.43) | MEN1KMT2AMITF | |
| SCHEMBL24072425 | 0.73 | GNAI3 (0.50) | — | |
| SCHEMBL18912138 | 0.72 | — | — | |
| SCHEMBL14828700 | 0.72 | — | — | |
| SCHEMBL4709409 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519393-B1 | SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS | EPIZYME INC (US) | 2022-05-18 | — | — | EP | disclosed |