Sugi Predict

Sugi Predict / Compounds / SCHEMBL24433726

SCHEMBL24433726

SCHEMBL24433726

CC(C)(C)c1ccc(N(C(C)(C)C)C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.39
▸ MAPT P10636 3/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ ALOX15 P16050 2/20 0.39
▸ HPGD P15428 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ CYP1A2 P05177 2/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ TSHR P16473 1/20 0.34
▸ NPC1 O15118 1/20 0.33
▸ PLA2G1B P04054 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ CASP3 P42574 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26196424 0.86 CYP1A2 (0.34) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL22181551 0.81 CYP1A2 (0.41) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL24848636 0.81 CYP1A2 (0.41) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL24237294 0.76 ALDH1A1 (0.39) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL24444043 0.75 KDM4E (0.39) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL24433644 0.74 ALDH1A1 (0.32) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL26194086 0.73 AR (0.39) ALDH1A1MAPTCYP1A2CYP2C19TSHR
SCHEMBL24433645 0.73 RXRA (0.36) ALDH1A1MAPTMEN1GAAKMT2A
SCHEMBL29630132 0.72 ALDH1A1 (0.48) ALDH1A1MAPTMEN1GAAPKM
SCHEMBL779415 0.72 ALDH1A1 (0.48) ALDH1A1MAPTMEN1GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 — — US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, LBR, C1R ALDH1A1 1177/4885MAPT 4119/4885MEN1 2979/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 ALDH1A1 1303/4885MAPT 3847/4885MEN1 2172/4885
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 ALDH1A1 102/4885MAPT 1458/4885MEN1 954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.