SCHEMBL24433645

SCHEMBL24433645

CC(C)(C)c1cc(-c2ccccc2)ccc1N(C(C)(C)C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RARB P10826 8/20 0.35
RARG P13631 8/20 0.35
RARA P10276 7/20 0.35
GAA P10253 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALOX5 P09917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26194086 0.86 AR (0.39) RARBRARGRARAALDH1A1MAPT
SCHEMBL26196423 0.80 MEN1 (0.34) RXRARXRBRARBRARGRARA
SCHEMBL28393472 0.80 MEN1 (0.39) RXRARXRBALDH1A1MEN1LMNA
SCHEMBL26196550 0.80 HSD17B1 (0.37) RXRARXRBGAAALDH1A1KDM4E
SCHEMBL24732286 0.78 MEN1 (0.35) RXRARXRBRARBRARGRARA
SCHEMBL27991629 0.77 RXRA (0.42) RXRARXRBRARBRARGGAA
SCHEMBL902111 0.74 ALDH1A1 (0.44) ALDH1A1KDM4EKMT2AKIF11CA2
SCHEMBL24732270 0.74 CYP1A2 (0.43) RXRBALDH1A1KDM4EMEN1MAPT
SCHEMBL24608696 0.73 RXRB (0.39) RXRARXRBRARBRARGRARA
SCHEMBL24433726 0.73 ALDH1A1 (0.39) GAAALDH1A1KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 US disclosed
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 US disclosed
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, LBR, C1R RXRA 362/4885RXRB 354/4885RARB 381/4885
US-20230142498-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 RXRA 2790/4885RXRB 2152/4885RARB 1734/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 RXRA 420/4885RXRB 295/4885RARB 995/4885
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 RXRA 4188/4885RXRB 3972/4885RARB 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.