Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26522334 | 0.81 | MCL1 (0.53) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL31590512 | 0.72 | MAPT (0.43) | ALDH1A1CYP2C9ALOX15HSD17B10BRAF | |
| SCHEMBL11955002 | 0.71 | ALDH1A1 (0.48) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL28838185 | 0.70 | ALDH1A1 (0.52) | ALDH1A1CYP2C9HSD17B10MAPK14MAPT | |
| Hydroquinone SCHEMBL28095978 | 0.68 | CA2 (0.45) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL11339706 | 0.67 | ALDH1A1 (0.52) | ALDH1A1LMNACYP2C9HTTHSD17B10 | |
| SCHEMBL10224686 | 0.67 | MCL1 (0.49) | TRPV1MCL1MAPT | |
| SCHEMBL23074859 | 0.66 | CYP2A6 (0.59) | ALDH1A1TYRHSD17B10GAAMAPT | |
| SCHEMBL19196145 | 0.66 | CA2 (0.50) | NR1I2ALDH1A1LMNACYP2C9MIF | |
| SCHEMBL28423964 | 0.65 | CA2 (0.46) | NR1I2ALDH1A1LMNACYP2C9MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220155287-A1 | SMALL MOLECULES TARGETING THE INTRINSICALLY DISORDERED STRUCTURAL ENSEMBLE OF ALPHA-SYNUCLEIN PROTECT AGAINST DIVERSE ALPHA-SYNUCLEIN MEDIATED DYSFUNCTIONS | UNIV CALIFORNIA (US) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220155287-A1 | SMALL MOLECULES TARGETING THE INTRINSICALLY DISORDERED STRUCTURAL ENSEMBLE OF ALPHA-SYNUCLEIN PROTECT AGAINST DIVERSE ALPHA-SYNUCLEIN MEDIATED DYSFUNCTIONS | SNCA, PARK7, SYNCRIP | NR1I2 2568/4885ALDH1A1 3157/4885LMNA 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.