Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891846 | 0.79 | CNR1 (0.42) | ALDH1A1SLC6A9HSD11B1 | |
| SCHEMBL22455050 | 0.77 | AR (0.47) | OPRM1OPRL1FFAR1CYP2D6CYP3A4 | |
| SCHEMBL28193878 | 0.74 | FFAR1 (0.38) | OPRM1OPRL1OPRD1OPRK1FFAR1 | |
| SCHEMBL28095083 | 0.73 | FFAR1 (0.37) | OPRM1OPRL1OPRD1OPRK1FFAR1 | |
| SCHEMBL29185211 | 0.73 | HSD11B1 (0.41) | OPRM1OPRL1OPRD1OPRK1FFAR1 | |
| SCHEMBL26607916 | 0.72 | AR (0.43) | OPRM1OPRL1OPRD1FFAR1CYP2C19 | |
| SCHEMBL8116829 | 0.71 | FFAR1 (0.39) | OPRM1OPRL1OPRD1OPRK1FFAR1 | |
| SCHEMBL24316045 | 0.71 | MEN1 (0.43) | CYP2D6CYP3A4ALDH1A1LMNA | |
| SCHEMBL15059997 | 0.70 | FFAR1 (0.44) | FFAR1CYP2D6CYP3A4CYP2C19USP2 | |
| SCHEMBL8452213 | 0.69 | USP2 (0.39) | OPRM1OPRL1OPRD1OPRK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | OPRM1 4412/4885OPRL1 3554/4885OPRD1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.