Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466296 | 1.00 | HPGD (0.43) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24435339 | 0.85 | LMNA (0.44) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24435294 | 0.84 | SCN3A (0.47) | HPGDALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL24434883 | 0.84 | SMN1; SMN2 (0.40) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24434781 | 0.84 | SMN1; SMN2 (0.40) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24435307 | 0.84 | SMN1; SMN2 (0.40) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24435129 | 0.84 | SMN1; SMN2 (0.39) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24434670 | 0.84 | SMN1; SMN2 (0.39) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL24435151 | 0.83 | SMN1; SMN2 (0.39) | HPGDALDH1A1HSD17B10ALOX15LMNA | |
| SCHEMBL31466364 | 0.83 | SMN1; SMN2 (0.39) | HPGDALDH1A1HSD17B10ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | HPGD 2543/4885ALDH1A1 4817/4885HSD17B10 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.