Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385406 | 0.81 | GFER (0.35) | MEN1KMT2ASLC18A3MAPK1SMN1; SMN2 | |
| SCHEMBL16480433 | 0.81 | CNR1 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1071244 | 0.81 | MAPK1 (0.50) | SLC18A3MAPK1SMN1; SMN2MAPTALOX5 | |
| SCHEMBL24434975 | 0.77 | PIK3CD (0.55) | MEN1KMT2ASLC18A3MAPK1ALOX5 | |
| SCHEMBL2899074 | 0.74 | MEN1 (0.50) | MEN1KMT2APIK3CDL3MBTL1KDM4E | |
| SCHEMBL17458687 | 0.73 | MAPK1 (0.45) | SLC18A3MAPK1SMN1; SMN2MAPTALOX5 | |
| SCHEMBL4019885 | 0.72 | SLC18A3 (0.42) | MEN1KMT2ASLC18A3MAPK1SMN1; SMN2 | |
| SCHEMBL3245667 | 0.72 | RAD52 (0.40) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL13380438 | 0.71 | MAPK1 (0.50) | SLC18A3MAPK1SMN1; SMN2MAPTALOX5 | |
| SCHEMBL21535460 | 0.69 | MAPK1 (0.39) | SLC18A3MAPK1SMN1; SMN2MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | MEN1 1347/4885KMT2A 4802/4885SLC18A3 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.