Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.31 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390134 | 0.80 | THRB (0.43) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL6385406 | 0.79 | GFER (0.35) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL6385038 | 0.76 | RAD52 (0.36) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL6384690 | 0.76 | RAD52 (0.36) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL6385931 | 0.74 | RAD52 (0.35) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL6383728 | 0.74 | THRB (0.41) | RAD52THRBGAAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6097647 | 0.73 | RAD52 (0.34) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL6220147 | 0.73 | RAD52 (0.50) | RAD52THRBGAAKDM4EMAPT | |
| SCHEMBL16480433 | 0.72 | CNR1 (0.42) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6706979 | 0.72 | RAD52 (0.53) | RAD52THRBGAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | claimed |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | LANG GERARD (FR) | 2004-05-13 | — | — | US | claimed |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-09-11 | — | — | US | claimed |
| EP-1341511-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL)PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 4 | L'OREAL (FR) | 2003-09-10 | — | — | EP | claimed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | claimed |
| EP-1263398-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-12-11 | — | — | EP | claimed |
| EP-1263397-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT | L'OREAL (FR) | 2002-12-11 | — | — | EP | claimed |
| EP-1263399-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-12-11 | — | — | EP | claimed |
| CN-1372458-A | Oxidation dyeing composition for keratinous fibres and dyeing method using said composition | OREAL (FR) | 2002-10-02 | — | — | CN | claimed |
| WO-2002045672-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL)PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 4 | L'OREAL (FR) | 2002-06-13 | — | — | WO | claimed |
| EP-1181005-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | claimed |
| EP-1181004-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | claimed |
| WO-2001066069-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066071-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066068-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066072-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066070-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| EP-1200052-B1 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | OREAL (FR) | 2010-05-26 | — | — | EP | disclosed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-20050097682-A9 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | L'OREAL S.A. (FR) | 2005-05-12 | — | — | US | disclosed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | disclosed |
| CN-1532193-A | Dimethyl-[1-(4-nitrophenyl) pyrrolidine-3-yl] amine | �ź㴫 | 2004-09-29 | — | — | CN | disclosed |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | LANG GERARD (FR) | 2004-05-13 | — | — | US | disclosed |
| US-20040088799-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 | L'OREAL S.A. (FR) | 2004-05-13 | — | — | US | disclosed |
| US-20040083559-A1 | Dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted at least in positions 2 and 3 | L'OREAL S.A. (FR) | 2004-05-06 | — | — | US | disclosed |
| US-20040078905-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | TERRANOVA ERIC (FR) | 2004-04-29 | — | — | US | disclosed |
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
| US-20040064902-A1 | Oxidatiton dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 and 5 | L'OREAL S.A. (FR) | 2004-04-08 | — | — | US | disclosed |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-09-11 | — | — | US | disclosed |
| EP-1341509-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITION 2 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| EP-1341510-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| EP-1341511-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL)PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 4 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| EP-1341508-A1 | DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED AT LEAST IN POSITIONS 2 AND 3 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| EP-1341507-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 5 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | disclosed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | disclosed |
| EP-1263398-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-12-11 | — | — | EP | disclosed |
| EP-1263399-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-12-11 | — | — | EP | disclosed |
| EP-1263397-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT | L'OREAL (FR) | 2002-12-11 | — | — | EP | disclosed |
| CN-1372459-A | Dyeing composition for keratinous fibres comprising a p-phenylenediamine derivative having a pyrrolidinyl group | OREAL (FR) | 2002-10-02 | — | — | CN | disclosed |
| WO-2002074269-A2 | DYEING COMPOSITIONS FOR KERATIN FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |
| WO-2002074259-A2 | DYEING COMPOSITIONS FOR KERATIN FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |
| WO-2002045668-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 5 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002045672-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL)PYRROLIDINES SUBSTITUTED IN POSITIONS 2 AND 4 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002045671-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITIONS 3 AND 4, AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002045670-A1 | OXIDATION DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED IN POSITION 2 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002045669-A1 | DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED AT LEAST IN POSITIONS 2 AND 3 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |
| EP-1181005-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | disclosed |
| EP-1181004-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001066069-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066069-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066072-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066070-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066071-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066068-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | KRT18, CDC73, DAO | RAD52 431/4885THRB 4103/4885GAA 4224/4885 |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | KRT18, CKAP4, KRTCAP2 | RAD52 697/4885THRB 4876/4885GAA 3893/4885 |
| US-20040088799-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 | PYCR1, COX5A, COX5B | RAD52 498/4885THRB 4574/4885GAA 4573/4885 |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, NDUFB5, NDUFB4 | RAD52 435/4885THRB 4030/4885GAA 4382/4885 |
| US-20040074013-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in positions 3 and 4, and dyeing method using same | KRT18, PYCR1, COX5A | RAD52 530/4885THRB 4594/4885GAA 4468/4885 |
| US-20040064902-A1 | Oxidatiton dyeing composition based on 1-(4-aminophenyl) pyrrolidines substituted in position 2 and 5 | COX5B, KRT18, PYCR1 | RAD52 631/4885THRB 4473/4885GAA 4466/4885 |
| US-20040078905-A1 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | PYCR1, KRT18, COX5A | RAD52 563/4885THRB 4663/4885GAA 4471/4885 |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, COXFA4L2 | RAD52 348/4885THRB 4421/4885GAA 3612/4885 |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, OAT, ACOX1 | RAD52 508/4885THRB 4100/4885GAA 4428/4885 |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, NDUFB5 | RAD52 421/4885THRB 4613/4885GAA 4105/4885 |
| US-20040083559-A1 | Dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted at least in positions 2 and 3 | KRT18, PYCR1, COX5A | RAD52 663/4885THRB 4554/4885GAA 4591/4885 |
| US-20050097682-A9 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | PYCR1, KRT18, COX5A | RAD52 563/4885THRB 4663/4885GAA 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.