Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.50 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244038 | 0.76 | KCNN3 (0.77) | KCNN3KCNN2POLBNPSR1MAPK1 | |
| SCHEMBL183069 | 0.75 | KCNN3 (0.80) | KCNN3KCNN2POLBNPSR1MAPK1 | |
| SCHEMBL2521840 | 0.72 | KCNN2 (0.55) | KCNN3KCNN2MAPTL3MBTL1NPSR1 | |
| SCHEMBL21357700 | 0.70 | KCNN2 (0.59) | KCNN3KCNN2POLBMAPTL3MBTL1 | |
| SCHEMBL2517763 | 0.70 | KCNN3 (0.54) | KCNN3KCNN2MAPTL3MBTL1NPSR1 | |
| SCHEMBL2516946 | 0.68 | KCNN3 (0.51) | KCNN3KCNN2MAPTL3MBTL1NPSR1 | |
| SCHEMBL2519463 | 0.68 | KCNN3 (0.51) | KCNN3KCNN2MAPTL3MBTL1NPSR1 | |
| SCHEMBL183176 | 0.67 | KCNN3 (1.00) | KCNN3KCNN2POLBMAPTL3MBTL1 | |
| SCHEMBL30421528 | 0.67 | KCNN3 (1.00) | KCNN3KCNN2POLBMAPTL3MBTL1 | |
| SCHEMBL182996 | 0.66 | KCNN3 (0.80) | KCNN3KCNN2POLBMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004246-A1 | PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004246-A1 | PURINYL DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | KCNJ2, KCNJ5, KCNJ3 | KCNN3 15/4885KCNN2 5/4885POLB 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.