Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 17/20 | 0.73 |
| ▸ | HPGD | P15428 | 12/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.63 |
| ▸ | TSHR | P16473 | 10/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.63 |
| ▸ | USP2 | O75604 | 4/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30556672 | 0.92 | ALDH1A1 (0.77) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL17518848 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL30212352 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL25561240 | 0.80 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL27246564 | 0.80 | ALDH1A1 (0.71) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL30212536 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL30417146 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL29782931 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL19558107 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL30057640 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | ALDH1A1 4817/4885HSD17B10 2073/4885HPGD 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.