Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435091 | 0.88 | ROCK2 (0.46) | ROCK2ROCK1LMNANPC1RAB9A | |
| SCHEMBL24435120 | 0.86 | AOC3 (0.45) | LMNANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL24434822 | 0.86 | MAPT (0.48) | RXFP1ROCK2ROCK1LMNARAB9A | |
| SCHEMBL24434861 | 0.85 | AOC3 (0.48) | ROCK2ROCK1LMNANPC1RAB9A | |
| SCHEMBL24435101 | 0.84 | ROCK1 (0.49) | ROCK2ROCK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24435150 | 0.84 | PDE5A (0.47) | ROCK2ROCK1LMNANPC1RAB9A | |
| SCHEMBL24434622 | 0.84 | SMN1; SMN2 (0.43) | LMNANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL24434817 | 0.83 | SCD (0.47) | LMNANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL24434682 | 0.82 | SMN1; SMN2 (0.46) | LMNANPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL24434604 | 0.82 | SCN3A (0.49) | ROCK2ROCK1CNR2SCN3ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | RXFP1 2740/4885ROCK2 3100/4885ROCK1 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.