SCHEMBL2443598

SCHEMBL2443598

Cc1cc(C2(c3ccc(Oc4cc(N)ccc4C(C)C)c(C)c3)c3ccccc3-c3ccccc32)ccc1Oc1cc(N)ccc1C(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
OPRK1 P41145 1/20 0.44
KMT2A Q03164 1/20 0.44
MAOA P21397 1/20 0.36
NPSR1 Q6W5P4 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PDK2 Q15119 2/20 0.32
P2RX3 P56373 3/20 0.31
P2RX2 Q9UBL9 3/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25251979 0.92 ESR1 (0.46) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL29418397 0.89 LMNA (0.46) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL2446277 0.89 LMNA (0.46) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL2445179 0.88 MAPT (0.54) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL29418392 0.88 MAPT (0.54) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL2440305 0.87 MEN1 (0.50) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL2440276 0.84 SMN1; SMN2 (0.50) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL2443593 0.83 ESR1 (0.44) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL2441739 0.83 ESR1 (0.44) ESR1ESR2SMN1; SMN2LMNAMAPT
SCHEMBL3874336 0.82 LMNA (0.42) ESR1ESR2SMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed