SCHEMBL25251979

SCHEMBL25251979

Cc1cc(C2(c3ccc(Oc4ccc(N)cc4C(C)C)c(C)c3)c3ccccc3-c3ccccc32)ccc1Oc1ccc(N)cc1C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
OPRK1 P41145 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PDK2 Q15119 2/20 0.32
P2RX3 P56373 4/20 0.32
P2RX2 Q9UBL9 4/20 0.32
CHRM5 P08912 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418397 0.95 LMNA (0.46) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2446277 0.95 LMNA (0.46) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2440276 0.93 SMN1; SMN2 (0.50) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2443598 0.92 ESR1 (0.45) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL29418392 0.89 MAPT (0.54) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2445179 0.89 MAPT (0.54) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2442386 0.88 LMNA (0.42) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2441823 0.86 SMN1; SMN2 (0.43) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL25277067 0.86 KDM4E (0.43) ESR1ESR2LMNAMAPTKDM4E
SCHEMBL2442533 0.85 MEN1 (0.51) ESR1ESR2LMNAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed