Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483900 | 0.78 | LOXL2 (0.56) | LOXL2CHRM2KCNH3 | |
| SCHEMBL7981962 | 0.78 | LOXL2 (0.47) | LOXL2CHRM2KCNH3ALDH1A1 | |
| SCHEMBL10483895 | 0.77 | LOXL2 (0.59) | LOXL2CHRM2KCNH3 | |
| SCHEMBL13509696 | 0.77 | ALDH1A1 (0.54) | CHRM2ALDH1A1MAOACYP2D6CYP2C19 | |
| SCHEMBL12880430 | 0.77 | LOXL2 (0.50) | LOXL2KCNH3 | |
| SCHEMBL12880427 | 0.74 | LOXL2 (0.53) | LOXL2KCNH3 | |
| SCHEMBL12880418 | 0.73 | LOXL2 (0.57) | LOXL2KCNH3 | |
| SCHEMBL7861380 | 0.72 | MAOA (0.71) | CHRM2MAOAHDAC3HDAC1HDAC2 | |
| SCHEMBL29380563 | 0.72 | MAOA (0.71) | CHRM2MAOAHDAC3HDAC1HDAC2 | |
| SCHEMBL640522 | 0.72 | MAOA (0.71) | CHRM2MAOAHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101453-A1 | COMPOUNDS AND METHODS FOR TREATING A CYTOKINE-MEDIATED DISEASE | Conservatoire National des Arts et Métiers (FR) | 2022-05-19 | — | — | WO | disclosed |