Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17916223 | 0.81 | PIK3CD (0.44) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL24437849 | 0.80 | ADH1A (0.43) | ACHEHRH4HRH3KMT2AMEN1 | |
| SCHEMBL13612632 | 0.78 | ACHE (0.40) | ACHEHRH4HRH3 | |
| SCHEMBL11932511 | 0.78 | PIK3CD (0.41) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL16625957 | 0.77 | PIK3CD (0.47) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL24437808 | 0.77 | PIK3CD (0.40) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL24437806 | 0.77 | PIK3CD (0.40) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL22507526 | 0.77 | PIK3CD (0.40) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL11932513 | 0.76 | PIK3CD (0.42) | PIK3CDHRH4HRH3KMT2AMEN1 | |
| SCHEMBL27045475 | 0.76 | ACHE (0.39) | ACHEHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101453-A1 | COMPOUNDS AND METHODS FOR TREATING A CYTOKINE-MEDIATED DISEASE | Conservatoire National des Arts et Métiers (FR) | 2022-05-19 | — | — | WO | disclosed |