Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612632 | 0.86 | ACHE (0.40) | ADH1AACHEADH1CHRH4HRH3 | |
| SCHEMBL27045475 | 0.84 | ACHE (0.39) | ADH1AACHEADH1CHRH4HRH3 | |
| SCHEMBL17055392 | 0.82 | ADH1A (0.40) | ADH1AADH1CHRH4HRH3MAPK1 | |
| SCHEMBL17055354 | 0.82 | ADH1A (0.40) | ADH1AADH1CHRH4HRH3MAPK1 | |
| SCHEMBL24437745 | 0.80 | ACHE (0.40) | ACHEHRH4HRH3MAPK1MEN1 | |
| SCHEMBL5253027 | 0.79 | ADH1A (0.52) | ADH1AADH1CHRH4HRH3MEN1 | |
| SCHEMBL25510772 | 0.79 | ADH1A (0.52) | ADH1AADH1CHRH4HRH3MEN1 | |
| SCHEMBL8272566 | 0.78 | HRH4 (0.40) | ADH1AACHEADH1CHRH4HRH3 | |
| SCHEMBL26730980 | 0.78 | ACHE (0.49) | ACHEALDH1A1 | |
| SCHEMBL3152072 | 0.77 | ACHE (0.34) | ADH1AACHEHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101453-A1 | COMPOUNDS AND METHODS FOR TREATING A CYTOKINE-MEDIATED DISEASE | Conservatoire National des Arts et Métiers (FR) | 2022-05-19 | — | — | WO | disclosed |