Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.76 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.60 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24438034 | 0.92 | TMPRSS4 (0.76) | TMPRSS4P2RX1ALOX15MEN1KMT2A | |
| SCHEMBL538439 | 0.87 | TMPRSS4 (1.00) | TMPRSS4P2RX1MEN1KMT2AP2RX4 | |
| SCHEMBL13812609 | 0.87 | TMPRSS4 (0.64) | TMPRSS4P2RX1ALOX15MEN1KMT2A | |
| SCHEMBL13593307 | 0.86 | P2RX1 (0.66) | TMPRSS4P2RX1ALOX15MEN1KMT2A | |
| SCHEMBL29024720 | 0.85 | TMPRSS4 (0.83) | TMPRSS4P2RX1MEN1KMT2AP2RX4 | |
| SCHEMBL2169619 | 0.84 | P2RX1 (1.00) | TMPRSS4P2RX1MEN1KMT2AP2RX4 | |
| SCHEMBL29454776 | 0.84 | P2RX1 (1.00) | TMPRSS4P2RX1MEN1KMT2AP2RX4 | |
| SCHEMBL24438058 | 0.84 | TMPRSS4 (0.67) | TMPRSS4P2RX1P2RX4P2RX7KCNMA1 | |
| SCHEMBL27764935 | 0.83 | KLKB1 (0.80) | TMPRSS4P2RX1ALOX15P2RX4P2RX7 | |
| SCHEMBL18341403 | 0.83 | TMPRSS4 (0.86) | TMPRSS4P2RX1ALOX15P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103572-A1 | COMPOUNDS AND METHODS OF INHIBITING BACTERIAL CHAPERONIN SYSTEMS | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-05-19 | — | — | WO | disclosed |