SCHEMBL29024720

SCHEMBL29024720

O=C(Nc1ccc(-c2ccccc2)cc1)c1cc(Cl)ccc1O

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TMPRSS4 Q9NRS4 9/20 0.83
P2RX1 P51575 10/20 0.77
P2RX4 Q99571 6/20 0.67
P2RX7 Q99572 6/20 0.67
KCNMA1 Q12791 4/20 0.65
SMO Q99835 1/20 0.59
MEN1 O00255 1/20 0.57
IKBKB O14920 1/20 0.57
CHUK O15111 1/20 0.57
KDR P35968 1/20 0.57
FLT3 P36888 1/20 0.57
KMT2A Q03164 1/20 0.57
MYLK Q15746 1/20 0.57
MAP4K5 Q9Y4K4 1/20 0.57
SLC2A1 P11166 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538439 0.91 TMPRSS4 (1.00) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL329189 0.89 TMPRSS4 (0.78) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL29454776 0.88 P2RX1 (1.00) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL2169619 0.88 P2RX1 (1.00) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL18341403 0.87 TMPRSS4 (0.86) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL13812568 0.86 TMPRSS4 (0.78) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL12189469 0.85 GRIK1 (0.67) TMPRSS4P2RX1SMOMEN1KMT2A
SCHEMBL24438367 0.85 TMPRSS4 (0.76) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL24438295 0.85 TMPRSS4 (0.76) TMPRSS4P2RX1P2RX4P2RX7KCNMA1
SCHEMBL30692667 0.85 TMPRSS4 (0.76) TMPRSS4P2RX1P2RX4P2RX7KCNMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354879-A Benzamide derivative and application thereof 中国药科大学 2023-06-30 CN disclosed