SCHEMBL7592166

SCHEMBL7592166

C=CC(=O)OCCNc1ccncc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
TSHR P16473 5/20 0.42
ALDH1A1 P00352 4/20 0.42
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP3A4 P08684 1/20 0.42
HSD17B10 Q99714 1/20 0.42
F2 P00734 5/20 0.40
BCHE P06276 1/20 0.39
HPGD P15428 1/20 0.39
MDM2 Q00987 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
FDPS P14324 1/20 0.37
POLB P06746 1/20 0.37
PKM P14618 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988048 0.84 THRB (0.57) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL22648161 0.81 MAPT (0.48) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL7633786 0.79 THRB (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL23409891 0.79 TSHR (0.44) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL31575054 0.79 F2 (0.43) CYP3A4F2BCHEMDM2FDPS
SCHEMBL22648042 0.78 SMN1; SMN2 (0.45) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL24439640 0.78 THRB (0.40) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL23463871 0.77 THRB (0.56) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL1224388 0.76 TSHR (0.50) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL30098565 0.75 THRB (0.54) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737887-B1 Method for preparing a silver halide emulsion FUJI PHOTO FILM CO LTD (JP) 2002-11-13 EP disclosed
US-6171775-B1 Silver halide emulsion and lightsensitive material including the same FUJI PHOTO FILM CO., LTD. (JP) 2001-01-09 US disclosed
US-6159677-A Silver halide emulsion and silver halide color lightsensitive material including the same FUJI PHOTO FILM, CO., LTD. (JP) 2000-12-12 US disclosed
US-6143483-A EMULSION EXCELLENT IN SENSITIVITY AND IN EACH OF SUPPRESSION OF DEPENDENCE ON A PROCESSING SOLUTION PH AND PRESERVABILITY OF LATENT IMAGE FUJI PHOTO FILM CO. (JP) 2000-11-07 US disclosed
EP-0567083-B1 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO LTD (JP) 1999-09-01 EP disclosed
EP-0576880-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1998-12-23 EP disclosed
US-5807665-A Silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1998-09-15 US disclosed
EP-0737887-A2 Silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1996-10-16 EP disclosed
US-5405738-A A perfect cubic silver halide grains are spectrally sensitized with sensitizing dyes; photosensitivity, contrast, high color density, image quality FUJI PHOTO FILM CO., LTD. (JP) 1995-04-11 US disclosed
US-5370984-A Containing an addition polymer FUJI PHOTO FILM CO., LTD. (JP) 1994-12-06 US disclosed
EP-0576880-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-01-05 EP disclosed
EP-0567083-A1 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-10-27 EP disclosed