Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439546 | 0.96 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL24439448 | 0.92 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1KDM4ENPC1MITF | |
| SCHEMBL24439543 | 0.79 | CCNT1 (0.32) | CCNT1CDK9 | |
| SCHEMBL2523197 | 0.71 | CYP1A2 (0.39) | SMN1; SMN2ALDH1A1KDM4EMAPTHTT | |
| SCHEMBL24439797 | 0.70 | HTT (0.33) | SMN1; SMN2HTTCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL24439838 | 0.70 | SMN1; SMN2 (0.30) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4TSHR | |
| SCHEMBL17523539 | 0.63 | HTR7 (0.41) | SMN1; SMN2ALDH1A1MAPTCCNT1CDK9 | |
| SCHEMBL17869465 | 0.63 | CHRNB2 (0.31) | CCNT1CDK9 | |
| SCHEMBL9869341 | 0.61 | POLB (0.38) | ALDH1A1KDM4ERAB9ACCNT1CDK9 | |
| SCHEMBL25274344 | 0.60 | CCNT1 (0.32) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022104206-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2022-05-19 | — | — | WO | disclosed |