Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24441059 | 0.89 | CSNK2A1 (0.38) | RIPK1PDE4DKMOPDE4AMEN1 | |
| SCHEMBL29672295 | 0.87 | KMO (0.36) | RECQLPDE4DKMOPDE4APDE4B | |
| SCHEMBL24439734 | 0.87 | KMO (0.36) | RECQLPDE4DKMOPDE4APDE4B | |
| SCHEMBL28744725 | 0.85 | LPAR1 (0.47) | PDE4DPDE4APDE4BPDE4CLPAR1 | |
| SCHEMBL29672126 | 0.84 | LPAR1 (0.33) | RIPK1RECQLPDE4DKMOPDE4A | |
| SCHEMBL24439314 | 0.84 | LPAR1 (0.33) | RIPK1RECQLPDE4DKMOPDE4A | |
| SCHEMBL29517377 | 0.84 | LPAR1 (0.41) | RIPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24439730 | 0.84 | LPAR1 (0.41) | RIPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24439618 | 0.84 | LPAR1 (0.41) | RIPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24439382 | 0.81 | SLCO1B1 (0.40) | RIPK1LPAR1FFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100623-A1 | NITROGEN-SUBSTITUTED HETEROCYCLIC THIOPHENE COMPOUNDS AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |