Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602253 | 1.00 | FFAR4 (0.34) | FFAR4LRRK2CDK2KDRPOLB | |
| SCHEMBL28755991 | 0.86 | SLCO1B1 (0.46) | FFAR4NEK2ABCB11SLCO1B1 | |
| SCHEMBL29517766 | 0.84 | ABCB11 (0.38) | FFAR4NEK2ABCB11SLCO1B1EGFR | |
| SCHEMBL24439737 | 0.84 | ABCB11 (0.38) | FFAR4NEK2ABCB11SLCO1B1EGFR | |
| SCHEMBL29672104 | 0.83 | POLB (0.36) | POLBABCB11SLCO1B1 | |
| SCHEMBL24439630 | 0.83 | POLB (0.36) | POLBABCB11SLCO1B1 | |
| SCHEMBL24439595 | 0.81 | NEK2 (0.36) | FFAR4LRRK2CDK2KDRNEK2 | |
| SCHEMBL29601754 | 0.81 | NEK2 (0.36) | FFAR4LRRK2CDK2KDRNEK2 | |
| SCHEMBL24441617 | 0.80 | FFAR4 (0.35) | FFAR4LRRK2POLBHDAC3CDK9 | |
| SCHEMBL24439358 | 0.79 | POLB (0.37) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022100625-A1 | NITROGEN-SUBSTITUTED AMINOCARBONATE THIOPHENE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |