Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31716571 | 0.86 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL1648901 | 0.81 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31324156 | 0.79 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Methane SCHEMBL8206725 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL29606219 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31324164 | 0.79 | MEN1 (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31324193 | 0.79 | MEN1 (0.73) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL15549325 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Methane SCHEMBL506242 | 0.78 | MEN1 (0.67) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31324185 | 0.78 | KDM4E (0.83) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |