Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168434 | 0.83 | CYP3A4 (0.42) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL168159 | 0.83 | MARS1 (0.57) | MARS1FAAHSMPD1GABRA2GABRB2 | |
| SCHEMBL4142817 | 0.81 | FAAH (0.52) | MARS1FAAHSMPD1GABRA2GABRB2 | |
| SCHEMBL6645241 | 0.73 | SLC6A2 (0.38) | MEN1KMT2A | |
| SCHEMBL167398 | 0.72 | SIGMAR1 (0.52) | GABRA2GABRB2SMN1; SMN2ALDH1A1CNR2 | |
| SCHEMBL1110698 | 0.72 | PPP1CA (0.50) | FAAHGABRA2GABRB2SLC16A3SLC16A1 | |
| SCHEMBL6053365 | 0.71 | MARS1 (0.66) | MARS1SMPD1SLC16A3SLC16A1RPA1 | |
| SCHEMBL342100 | 0.70 | MARS1 (0.68) | MARS1FAAHSMPD1GABRA2GABRB2 | |
| SCHEMBL29419099 | 0.70 | MARS1 (0.68) | MARS1FAAHSMPD1GABRA2GABRB2 | |
| SCHEMBL168942 | 0.69 | SLC5A1 (0.48) | GABRA2GABRB2RPA1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761490-B1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2011-09-07 | — | — | EP | disclosed |