SCHEMBL24445387

SCHEMBL24445387

Nc1ccnc(Cl)c1Sc1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
PKM P14618 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
DHFR P00374 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HAO1 Q9UJM8 1/20 0.38
FBP1 P09467 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
THRB P10828 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
TYMS P04818 1/20 0.36
HTT P42858 1/20 0.35
DYRK1A Q13627 1/20 0.35
NCF1 P14598 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565590 1.00 NR4A2 (0.41) NR4A2ALDH1A1MAPTPKMKDM4E
SCHEMBL25173193 0.81 NR4A2 (0.38) NR4A2ALDH1A1KDM4ESMN1; SMN2THRB
SCHEMBL444075 0.79 KDM4E (0.40) NR4A2ALDH1A1MAPTKDM4ELMNA
SCHEMBL8564814 0.77 MAPT (0.45) ALDH1A1MAPTPKMKDM4ELMNA
SCHEMBL14471748 0.70 PKM (0.50) ALDH1A1MAPTPKMKDM4ELMNA
SCHEMBL1743914 0.70 ALDH1A1 (0.38) NR4A2ALDH1A1PKMKDM4ELMNA
SCHEMBL31120582 0.69 POLB (0.47) ALDH1A1LMNAL3MBTL1SMN1; SMN2KMT2A
SCHEMBL29543966 0.69 RHEB (0.55) ALDH1A1MAPTPKMKDM4ELMNA
SCHEMBL6915666 0.69 RHEB (0.55) ALDH1A1MAPTPKMKDM4ELMNA
SCHEMBL5612266 0.68 HAO1 (0.44) ALDH1A1MAPTPKMKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4329463-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-02-28 EP disclosed
EP-4001287-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-01-17 EP disclosed
CN-114539322-A Organic electroluminescent material and device 环球展览公司 2022-05-27 CN disclosed
EP-4001287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-05-25 EP disclosed