Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566405 | 0.77 | CYP1A2 (0.50) | HTTLMNAALDH1A1TSHR | |
| SCHEMBL24445387 | 0.77 | NR4A2 (0.41) | MAPTHTTHAO1LMNAKDM4E | |
| SCHEMBL29565590 | 0.77 | NR4A2 (0.41) | MAPTHTTHAO1LMNAKDM4E | |
| SCHEMBL8321620 | 0.77 | HAO1 (0.45) | MAPTHAO1LMNAL3MBTL1KMT2A | |
| SCHEMBL8570726 | 0.75 | PDE4A (0.42) | MAPTHTTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6915666 | 0.75 | RHEB (0.55) | MAPTHAO1LMNAKDM4ENPSR1 | |
| SCHEMBL29543966 | 0.75 | RHEB (0.55) | MAPTHAO1LMNAKDM4ENPSR1 | |
| SCHEMBL5612266 | 0.74 | HAO1 (0.44) | MAPTHTTHAO1LMNAKDM4E | |
| SCHEMBL30548744 | 0.73 | RHEB (0.53) | MAPTHTTHAO1LMNAKDM4E | |
| SCHEMBL11778526 | 0.68 | ALDH1A1 (0.48) | HAO1LMNAALDH1A1PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |