SCHEMBL28126809

SCHEMBL28126809

COC(=O)CNc1cccc(NC(C)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.57
NR4A1 P22736 1/20 0.57
RAB9A P51151 1/20 0.57
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 3/20 0.53
HSD17B10 Q99714 2/20 0.53
CYP1A2 P05177 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.51
TSHR P16473 2/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11702794 0.84 POLB (0.54) POLBNR4A1RAB9AMEN1KMT2A
SCHEMBL24445558 0.84 MEN1 (0.53) POLBRAB9AMEN1KMT2AALDH1A1
SCHEMBL29613642 0.84 MEN1 (0.53) POLBRAB9AMEN1KMT2AALDH1A1
SCHEMBL14997387 0.82 POLB (0.58) POLBNR4A1RAB9AMEN1KMT2A
SCHEMBL11385963 0.82 RAB9A (0.58) POLBNR4A1RAB9AMEN1KMT2A
SCHEMBL1901172 0.80 ALDH1A1 (0.76) POLBNR4A1RAB9AMEN1KMT2A
SCHEMBL9779996 0.80 MAPT (0.56) POLBRAB9AMEN1KMT2AALDH1A1
SCHEMBL6904254 0.80 ALDH1A1 (0.51) RAB9AMEN1KMT2AALDH1A1CYP1A2
SCHEMBL3016054 0.80 RAB9A (0.69) POLBNR4A1RAB9AMEN1KMT2A
SCHEMBL28134476 0.79 POLB (0.55) POLBNR4A1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104559287-B Disperse dye compound as well as preparation method and application thereof 浙江龙盛集团股份有限公司 2017-02-22 CN disclosed