Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231794 | 1.00 | SCN9A (0.57) | SCN9AALDH1A1MAPTRECQLGPR84 | |
| 1-Methyltryptophan SCHEMBL19992 | 0.88 | MAPT (0.71) | SCN9AALDH1A1MAPTRECQLGPR84 | |
| (L)-1-Methyltryptophan SCHEMBL19993 | 0.88 | MAPT (0.71) | SCN9AALDH1A1MAPTRECQLGPR84 | |
| Indoximod SCHEMBL934800 | 0.88 | MAPT (0.71) | SCN9AALDH1A1MAPTRECQLGPR84 | |
| Indoximod SCHEMBL29349777 | 0.88 | MAPT (0.71) | SCN9AALDH1A1MAPTRECQLGPR84 | |
| 1-Methyltryptophan SCHEMBL14202956 | 0.88 | MAPT (0.71) | SCN9AALDH1A1MAPTRECQLGPR84 | |
| SCHEMBL19846989 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTRECQLGPR84HTR2A | |
| SCHEMBL14338216 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTRECQLGPR84HTR2A | |
| SCHEMBL17306338 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTRECQLGPR84HTR2A | |
| Indoximod SCHEMBL23668055 | 0.87 | MAPT (0.69) | SCN9AALDH1A1MAPTRECQLGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613420-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2022-05-25 | — | — | EP | disclosed |