Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ICMT | O60725 | 8/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29486510 | 1.00 | PKM (0.62) | PKMICMTSCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24445971 | 0.89 | ICMT (0.56) | PKMICMTALDH1A1KMT2ALMNA | |
| SCHEMBL29486509 | 0.85 | ICMT (0.72) | PKMICMTSCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24445947 | 0.85 | ICMT (0.72) | PKMICMTSCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23701735 | 0.84 | TSHR (0.61) | ICMTSCN9AALDH1A1KMT2ALMNA | |
| SCHEMBL29486507 | 0.83 | PKM (0.60) | PKMICMTSCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29486518 | 0.83 | PKM (0.60) | PKMICMTSCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24445993 | 0.83 | PKM (0.60) | PKMICMTSCN9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21808846 | 0.83 | PKM (0.70) | PKMICMTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5177499 | 0.82 | PKM (0.68) | PKMSMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4001414-A1 | NONHUMAN ANIMAL AND USE FOR SAME | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-05-25 | — | — | EP | disclosed |