Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24446014 | 0.89 | PKM (0.62) | ICMTKDM4EPKMNR4A1ALDH1A1 | |
| SCHEMBL29486510 | 0.89 | PKM (0.62) | ICMTKDM4EPKMNR4A1ALDH1A1 | |
| SCHEMBL30098548 | 0.86 | NR4A2 (0.62) | ICMTKDM4EPKMNR4A2ALDH1A1 | |
| SCHEMBL23718989 | 0.86 | NR4A2 (0.62) | ICMTKDM4EPKMNR4A2ALDH1A1 | |
| SCHEMBL23701735 | 0.85 | TSHR (0.61) | ICMTKDM4EMTNR1ANR4A1MTNR1B | |
| SCHEMBL23701740 | 0.82 | ICMT (0.55) | ICMTKDM4EPKMMTNR1ANR4A2 | |
| SCHEMBL21255987 | 0.82 | MTNR1A (0.59) | ICMTKDM4EPKMMTNR1ANR4A2 | |
| SCHEMBL2083266 | 0.82 | ALDH1A1 (0.51) | ICMTKDM4EPKMMTNR1ANR4A1 | |
| SCHEMBL23701799 | 0.81 | ICMT (0.62) | ICMTKDM4EMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL853729 | 0.80 | NPSR1 (0.68) | KDM4ENR4A1ALDH1A1HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |
| EP-4001414-A1 | NONHUMAN ANIMAL AND USE FOR SAME | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-05-25 | — | — | EP | disclosed |