Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 14/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.63 |
| ▸ | FAP | Q12884 | 11/20 | 0.44 |
| ▸ | PREP | P48147 | 3/20 | 0.41 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.41 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760537 | 1.00 | DPP4 (0.63) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL16330589 | 0.84 | DPP4 (0.44) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL16670795 | 0.84 | DPP4 (0.57) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL15832763 | 0.83 | DPP4 (0.48) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL10057905 | 0.81 | DPP4 (0.59) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2769142 | 0.81 | DPP4 (0.59) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL12001763 | 0.80 | ACE (0.41) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL18308997 | 0.79 | DPP4 (0.41) | DPP4DPP7DPP8DPP9XPNPEP1 | |
| SCHEMBL4409965 | 0.79 | DPP4 (0.63) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL10056816 | 0.79 | DPP4 (0.63) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001272-A1 | NMDA ANTAGONIST PRODRUGS | Astrazeneca AB (SE) | 2022-05-25 | — | — | EP | disclosed |