Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2345060 | 0.92 | HTT (0.36) | HTTPLAUSMN1; SMN2 | |
| SCHEMBL3237838 | 0.91 | HTT (0.35) | HTTPLAUSMN1; SMN2ALDH1A1 | |
| SCHEMBL8408754 | 0.90 | HTT (0.39) | HTTPLAUALDH1A1 | |
| SCHEMBL8408794 | 0.90 | HTT (0.39) | HTTPLAUALDH1A1 | |
| SCHEMBL7979231 | 0.89 | PDK2 (0.37) | HTTPLAUSMN1; SMN2 | |
| SCHEMBL8407690 | 0.88 | HTT (0.41) | HTTPLAU | |
| SCHEMBL3138415 | 0.87 | HTT (0.37) | HTTPLAU | |
| SCHEMBL7632172 | 0.86 | HTT (0.36) | HTTPLAUALDH1A1 | |
| SCHEMBL8666882 | 0.86 | HTT (0.36) | HTTPLAUSMN1; SMN2ALDH1A1 | |
| SCHEMBL6671379 | 0.86 | HTT (0.36) | HTTPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | FMC CORPORATION | 2010-06-17 | — | — | US | disclosed |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | FMC CORPORATION | 2010-06-17 | — | — | US | disclosed |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | FMC CORPORATION | 2010-06-17 | — | — | US | disclosed |
| US-7671201-B2 | Phenyl substituted cyclic derivatives | FMC CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671201-B2 | Phenyl substituted cyclic derivatives | FMC CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671201-B2 | Phenyl substituted cyclic derivatives | FMC CORPORATION (US) | 2010-03-02 | — | — | US | disclosed |
| EP-1620401-A4 | PHENYL SUBSTITUTED CYCLIC DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-08-13 | — | — | EP | disclosed |
| WO-2006130403-A1 | PHENYLALKYL SUBSTITUTED HETEROARYL DEVIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-12-07 | — | — | WO | disclosed |
| US-20060270726-A1 | Phenyl substituted cyclic derivatives | FMC CORPORATION | 2006-11-30 | — | — | US | disclosed |
| EP-1620401-A2 | PHENYL SUBSTITUTED CYCLIC DERIVATIVES | FMC CORPORATION (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099145-A2 | PHENYL SUBSTITUTED CYCLIC DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5952386-A | EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996033160-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270726-A1 | Phenyl substituted cyclic derivatives | DDT, L3MBTL4, L3MBTL3 | HTT 4802/4885PLAU 4792/4885SMN1; SMN2 2541/4885 |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | DDT, CRYAA, CYP19A1 | HTT 2985/4885PLAU 4867/4885SMN1; SMN2 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.