Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450119 | 0.83 | GRIA1 (0.36) | GRIA1GRIA2GRIA4GRIK5THRA | |
| SCHEMBL24449950 | 0.76 | THRA (0.65) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL13384415 | 0.73 | HPGD (0.66) | HPGDMAPK1 | |
| SCHEMBL13384412 | 0.73 | MAPK1 (0.41) | GRIA1GRIA2GRIA4GRIK5HPGD | |
| SCHEMBL13384443 | 0.72 | SMN1; SMN2 (0.40) | GRIA1GRIA2GRIA4GRIK5CYP2C9 | |
| SCHEMBL24449323 | 0.71 | HSP90AA1 (0.34) | THRATHRB | |
| SCHEMBL12341287 | 0.69 | HTT (0.44) | CYP2C9HPGD | |
| SCHEMBL20870268 | 0.69 | GRIA1 (0.38) | GRIA1GRIA2GRIA4GRIK5CYP2C9 | |
| SCHEMBL13384449 | 0.69 | GRIA1 (0.41) | GRIA1GRIA2GRIA4GRIK5CYP2C9 | |
| SCHEMBL24449319 | 0.68 | THRA (0.31) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | THRA, THRB, TSHR | GRIA1 771/4885GRIA2 1444/4885GRIA4 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.