Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24449316 | 0.76 | PTGDR2 (0.37) | THRATHRB | |
| SCHEMBL24449322 | 0.73 | THRA (0.63) | THRATHRB | |
| SCHEMBL24449323 | 0.71 | HSP90AA1 (0.34) | THRATHRB | |
| SCHEMBL38650588 | 0.70 | NPBWR1 (0.37) | — | |
| SCHEMBL24449325 | 0.68 | GRIA1 (0.39) | THRATHRB | |
| SCHEMBL2920651 | 0.66 | THRA (0.57) | THRATHRB | |
| SCHEMBL2922891 | 0.64 | THRB (0.68) | THRATHRB | |
| SCHEMBL28667325 | 0.62 | THRB (0.42) | THRATHRB | |
| SCHEMBL21749380 | 0.61 | NPBWR1 (0.47) | THRATHRB | |
| SCHEMBL29488647 | 0.61 | THRA (0.32) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | THRA, THRB, TSHR | THRA 1/4885THRB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.