Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634878 | 1.00 | THRB (0.71) | THRBTHRA | |
| SCHEMBL19859414 | 0.88 | THRB (0.79) | THRBTHRA | |
| SCHEMBL19859402 | 0.87 | THRB (0.65) | THRBTHRA | |
| SCHEMBL19859392 | 0.87 | THRB (0.77) | THRBTHRA | |
| SCHEMBL24450034 | 0.87 | THRB (0.53) | THRBTHRA | |
| SCHEMBL31347910 | 0.87 | THRB (0.53) | THRBTHRA | |
| SCHEMBL29074253 | 0.86 | THRB (0.66) | THRBTHRA | |
| SCHEMBL19859380 | 0.86 | THRB (0.76) | THRBTHRA | |
| SCHEMBL24450002 | 0.85 | THRB (0.52) | THRBTHRA | |
| SCHEMBL19859808 | 0.85 | THRB (0.74) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | THRA, THRB, TSHR | THRB 2/4885THRA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.