Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 18/20 | 0.52 |
| ▸ | THRA | P10827 | 17/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450034 | 0.90 | THRB (0.53) | THRBTHRALMNAL3MBTL1 | |
| SCHEMBL31347910 | 0.90 | THRB (0.53) | THRBTHRALMNAL3MBTL1 | |
| SCHEMBL31634878 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL24449333 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL24450001 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL24449952 | 0.82 | THRB (0.55) | THRBTHRA | |
| SCHEMBL282942 | 0.82 | THRB (0.45) | THRBTHRA | |
| SCHEMBL3160054 | 0.80 | THRB (0.71) | THRBTHRA | |
| SCHEMBL283282 | 0.79 | THRB (0.47) | THRBTHRALMNAL3MBTL1 | |
| SCHEMBL27702904 | 0.78 | THRB (0.48) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | THRA, THRB, TSHR | THRB 2/4885THRA 1/4885LMNA 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.