Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25514871 | 0.99 | PRKCA (0.56) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL15211586 | 0.97 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL17502440 | 0.97 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL15211803 | 0.97 | PRKCA (0.55) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL27306508 | 0.97 | PRKCA (0.57) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL21373211 | 0.96 | ALDH1A1 (0.61) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL21373212 | 0.96 | ALDH1A1 (0.61) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL21235636 | 0.96 | ALDH1A1 (0.61) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL21373207 | 0.96 | ALDH1A1 (0.61) | PRKCAPRKCEPRKCQPRKCDMAPT | |
| SCHEMBL21373214 | 0.96 | ALDH1A1 (0.61) | PRKCAPRKCEPRKCQPRKCDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381303-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | AKAGERA MEDICINES, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230381303-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | AKAGERA MEDICINES, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230126953-A1 | IONIZABLE CATIONIC LIPIDS | AKAGERA MEDICINES, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230126953-A1 | IONIZABLE CATIONIC LIPIDS | AKAGERA MEDICINES, INC. (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220411394-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | AKAGERA MEDICINES, INC. (US) | 2022-12-29 | — | — | US | disclosed |
| US-20220162521-A1 | IONIZABLE CATIONIC LIPIDS | AKAGERA MEDICINES, INC. | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411394-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | ASGR1, LDLR, CD2BP2 | PRKCA 1605/4885PRKCE 3343/4885PRKCQ 2026/4885 |
| US-20230381303-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | PHOSPHO1, PTDSS1, PTDSS2 | PRKCA 1104/4885PRKCE 2723/4885PRKCQ 1912/4885 |
| US-20220162521-A1 | IONIZABLE CATIONIC LIPIDS | PHOSPHO1, LIPA, ABHD16A | PRKCA 1018/4885PRKCE 1673/4885PRKCQ 914/4885 |
| US-20230126953-A1 | IONIZABLE CATIONIC LIPIDS | PHOSPHO1, LIPA, ABHD16A | PRKCA 1018/4885PRKCE 1673/4885PRKCQ 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.