Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | ATR | Q13535 | 19/20 | 0.51 |
| ▸ | ATRIP | Q8WXE1 | 16/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516408 | 0.85 | PIK3CD (0.52) | PIK3CDPIK3CAATRATRIPCHEK1 | |
| SCHEMBL30629341 | 0.79 | PIK3CD (0.58) | PIK3CDPIK3CAATRATRIPCHEK1 | |
| SCHEMBL2127456 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPCHEK1 | |
| SCHEMBL28539899 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPCHEK1 | |
| SCHEMBL29442179 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPCHEK1 | |
| SCHEMBL28539901 | 0.79 | ATR (0.55) | PIK3CDPIK3CAATRATRIPCHEK1 | |
| SCHEMBL30386045 | 0.78 | PIK3C3 (0.46) | PIK3CDPIK3CAATRATRIPMTOR | |
| SCHEMBL30386169 | 0.78 | PIK3C3 (0.46) | PIK3CDPIK3CAATRATRIPMTOR | |
| SCHEMBL11983520 | 0.77 | CCR1 (0.46) | — | |
| SCHEMBL29261326 | 0.77 | PIK3CA (0.51) | PIK3CDPIK3CAATRATRIPCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162191-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162191-A1 | SMALL MOLECULE MODULATORS OF IL-17 | IL17A, IL15, IL2 | PIK3CD 4249/4885PIK3CA 4128/4885ATR 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.