Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 10/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 7/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386045 | 1.00 | PIK3C3 (0.46) | PIK3C3PIK3CDPIK3CAATRATRIP | |
| SCHEMBL30516408 | 0.91 | PIK3CD (0.52) | PIK3C3PIK3CDPIK3CAATRATRIP | |
| SCHEMBL24453719 | 0.78 | PIK3CD (0.52) | PIK3CDPIK3CAATRATRIPMTOR | |
| SCHEMBL30288871 | 0.72 | PIK3C3 (0.52) | PIK3C3PIK3CAATRATRIPMTOR | |
| SCHEMBL2127456 | 0.72 | ATR (0.55) | PIK3C3PIK3CDPIK3CAATRATRIP | |
| SCHEMBL28539899 | 0.72 | ATR (0.55) | PIK3C3PIK3CDPIK3CAATRATRIP | |
| SCHEMBL28539901 | 0.72 | ATR (0.55) | PIK3C3PIK3CDPIK3CAATRATRIP | |
| SCHEMBL29442179 | 0.72 | ATR (0.55) | PIK3C3PIK3CDPIK3CAATRATRIP | |
| SCHEMBL11983520 | 0.70 | CCR1 (0.46) | — | |
| SCHEMBL29261233 | 0.70 | PIK3CA (0.51) | PIK3CDPIK3CAATRATRIPMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076167-A1 | INHIBITOR OF BTK AND MUTANTS THEREOF | NEWAVE PHARMACEUTICAL INC. (US) | 2023-05-04 | — | — | WO | disclosed |