Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15932233 | 0.89 | MAPT (0.39) | POLBOPRM1HDAC1HDAC2MAPT | |
| SCHEMBL24457797 | 0.86 | POLB (0.40) | POLBALDH1A1HDAC1HDAC2MAPT | |
| SCHEMBL10205157 | 0.84 | KMT2A (0.49) | DPP4DPP8POLBALDH1A1HDAC1 | |
| SCHEMBL10265114 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL16808292 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL8597022 | 0.82 | ATM (0.42) | POLBMAPTKMT2ATSHR | |
| SCHEMBL7828421 | 0.82 | ATM (0.42) | POLBMAPTKMT2ATSHR | |
| Water SCHEMBL8600954 | 0.81 | ATM (0.42) | POLBMAPTKMT2ATSHR | |
| SCHEMBL8626971 | 0.81 | POLB (0.38) | POLBALDH1A1HDAC1HDAC2MAPT | |
| SCHEMBL8600205 | 0.81 | POLB (0.40) | POLBALDH1A1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9677112-B2 | β-lactamase substrates and methods of their use for the diagnosis of tuberculosis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-06-13 | — | — | US | disclosed |
| US-9677112-B2 | β-lactamase substrates and methods of their use for the diagnosis of tuberculosis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150167048-A1 | BETA-LACTAMASE SUBSTRATES AND METHODS OF THEIR USE FOR THE DIAGNOSIS OF TUBERCULOSIS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150167048-A1 | BETA-LACTAMASE SUBSTRATES AND METHODS OF THEIR USE FOR THE DIAGNOSIS OF TUBERCULOSIS | PGLS, ENGASE, BPHL | DPP4 910/4885DPP8 593/4885POLB 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.