Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20621321 | 0.74 | NOS2 (0.48) | NOS2NOS3 | |
| SCHEMBL20621287 | 0.74 | TSHR (0.41) | NOS2NOS3 | |
| SCHEMBL23583849 | 0.70 | NOS2 (0.35) | NOS2NOS3 | |
| SCHEMBL25027836 | 0.70 | NOS2 (0.45) | NOS2NOS3 | |
| SCHEMBL11888061 | 0.69 | NOS3 (0.42) | NOS2NOS3 | |
| SCHEMBL10873419 | 0.69 | NOS3 (0.42) | NOS2NOS3 | |
| SCHEMBL24455242 | 0.69 | NOS2 (0.43) | NOS2NOS3 | |
| SCHEMBL26036992 | 0.68 | NR3C2 (0.43) | NOS2NOS3 | |
| SCHEMBL21567478 | 0.67 | CCR1 (0.35) | NOS2NOS3 | |
| SCHEMBL12051932 | 0.67 | MAPT (0.36) | NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109242-A1 | PROCESS FOR PREPARING 7-CHLORO-6-FLUORO-1-(2-ISOPROPYL-4-METHYLPYRIDIN-3- YL)PYRIDOF[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE | AMGEN INC. (US) | 2022-05-27 | — | — | WO | disclosed |