Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 7/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ADM2 | Q7Z4H4 | 4/20 | 0.35 |
| ▸ | CALCB | P10092 | 4/20 | 0.35 |
| ▸ | RAMP1 | O60894 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30884885 | 1.00 | CALCA (0.45) | CALCAIDH1CALCRLNR1H2RXRA | |
| SCHEMBL24447577 | 0.89 | CALCA (0.45) | CALCAIDH1CALCRLNR1H2RXRA | |
| SCHEMBL30599281 | 0.84 | NR1H2 (0.48) | NR1H2RXRANR1H3KDM1A | |
| SCHEMBL30599282 | 0.84 | NR1H2 (0.48) | NR1H2RXRANR1H3KDM1A | |
| SCHEMBL24403239 | 0.84 | NR1H2 (0.48) | NR1H2RXRANR1H3KDM1A | |
| SCHEMBL24403238 | 0.84 | NR1H2 (0.48) | NR1H2RXRANR1H3KDM1A | |
| SCHEMBL25757023 | 0.82 | CALCA (0.39) | CALCACALCRLADM2CALCBRAMP1 | |
| SCHEMBL30890451 | 0.81 | OPRM1 (0.45) | CALCANR1H2RXRANR1H3KDM1A | |
| SCHEMBL27245104 | 0.81 | OPRM1 (0.45) | CALCANR1H2RXRANR1H3KDM1A | |
| SCHEMBL24459334 | 0.81 | CALCA (0.36) | CALCACALCRLADM2CALCBRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |