Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797274 | 0.86 | RXFP1 (0.54) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL11055173 | 0.85 | TAS2R14 (0.60) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL5166111 | 0.83 | CYP1A2 (0.60) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL28141674 | 0.82 | TAS2R14 (0.57) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL18615673 | 0.82 | ALDH1A1 (0.54) | MAPTKMT2AMEN1HTTTAS2R14 | |
| SCHEMBL2096162 | 0.81 | MAPT (0.51) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL4463318 | 0.81 | TAS2R14 (0.52) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL8346848 | 0.79 | MAPT (0.56) | MAPTKMT2AMEN1HTTTSHR | |
| SCHEMBL29645247 | 0.79 | HPGD (0.75) | MAPTKMT2AMEN1TSHRHPGD | |
| SCHEMBL29645245 | 0.79 | HPGD (0.75) | MAPTKMT2AMEN1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109363-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |