Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166111 | 0.87 | CYP1A2 (0.60) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL11055173 | 0.85 | TAS2R14 (0.60) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL28141674 | 0.82 | TAS2R14 (0.57) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL14285769 | 0.81 | TAS2R14 (0.50) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL24459355 | 0.81 | MAPT (0.54) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL1273833 | 0.78 | GAA (0.70) | TAS2R14GAABRAFHTTRAB9A | |
| SCHEMBL18763038 | 0.78 | ALDH1A1 (0.53) | TAS2R14MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL31394374 | 0.78 | TAS2R14 (0.50) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL24225035 | 0.78 | TGM2 (0.58) | TAS2R14MEN1KMT2ACYP1A2GAA | |
| SCHEMBL29560526 | 0.78 | ALDH1A1 (0.53) | TAS2R14MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045083-A2 | COMBINATION THERAPY FOR NEUROPROTECTION | S.H. PHARMA., LTD (KR) | 2009-04-09 | — | — | WO | claimed |