SCHEMBL244606

SCHEMBL244606

C1=Cc2ccccc2ON=C1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
TRPA1 O75762 1/20 0.32
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29757278 0.98 KDM4E (0.36) KDM4EMEN1ALDH1A1MAPTKMT2A
Hydrochloric Acid SCHEMBL8480733 0.98 KDM4E (0.36) KDM4EMEN1ALDH1A1MAPTKMT2A
Methylene Chloride SCHEMBL27481165 0.92 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
Oxalic Acid SCHEMBL10499933 0.89 MEN1 (0.32) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL11830480 0.89 P2RX4 (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
Urea SCHEMBL8887498 0.89 KDM4E (0.35) KDM4EMEN1ALDH1A1MAPTKMT2A
Acetic Acid SCHEMBL25341096 0.88 TRPA1 (0.31) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL9268154 0.86 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
Fumaric Acid SCHEMBL11602682 0.85 ALDH1A1 (0.38) KDM4EMEN1ALDH1A1MAPTKMT2A
Fumaric Acid SCHEMBL11602668 0.85 ALDH1A1 (0.38) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2170 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4686476-A1 PHOSPHOINOSITIDE 3 KINASE (PI3K) INHIBITOR FOR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES Klostermeier, Stefanie (DE) 2026-02-04 EP claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-119954707-A Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof 云南大学 2025-05-09 CN claimed
CN-119859127-A Benzooxazepines and benzoxazoles Synthesis method and application of class compound 东北林业大学 2025-04-22 CN claimed
CN-119456369-A Spraying positioning method of fluorescent agent on end face of copper foil coil 南京龙电华鑫新能源材料产业技术研究院有限公司 2025-02-18 CN claimed
CN-118724885-A Benzoxazepine-diacid ester molecular hybridization derivative for inhibiting programmed cell necrosis and application thereof 中国人民解放军海军军医大学 2024-10-01 CN claimed
CN-118700734-A Carbon band composition for improving transfer adaptability and definition and preparation and transfer method thereof 湖南鼎一致远科技发展股份有限公司 2024-09-27 CN claimed
US-20240300931-A1 Composition and Methods for Treating Attention Deficit Disorders LIPPA ARNOLD STAN (US) 2024-09-12 US claimed
WO-2024102758-A2 N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2024-05-16 WO claimed
CN-117965021-A Pure-color 3D printing nylon powder and preparation method thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
EP-0615749-A2 Use of NMDA antagonists for the treatment of pain VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-09-21 EP claimed
EP-0440704-A1 COMPOSITIONS FOR TREATING TOBACCO WITHDRAWEL SYMPTOMS. MASSACHUSETTS INST TECHNOLOGY (US) 1991-08-14 EP claimed
EP-0107930-B1 FUSED AROMATIC OXAZEPINONES AND SULPHUR ANALOGUES THEREOF AND THEIR PREPARATION AND USE IN COUNTERACTING HISTAMINE A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) 1990-11-28 EP claimed
EP-0386117-A1 TREATING PREMENSTRUAL OR LATE LUTEAL PHASE SYNDROME MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-09-12 EP claimed
EP-0376633-A2 Benzoxazepine derivatives SUNTORY LIMITED (JP) 1990-07-04 EP claimed
WO-1990004387-A2 COMPOSITIONS FOR TREATING TOBACCO WITHDRAWAL SYMPTOMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1990-05-03 WO claimed
EP-0144729-B1 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-11-08 EP claimed
WO-1989003692-A1 TREATING PREMENSTRUAL OR LATE LUTEAL PHASE SYNDROME MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1989-05-05 WO claimed
EP-0300356-A1 5-Aryl-11-substituted-5H, 11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-01-25 EP claimed
US-4041048-A ANTIINFLAMMATORY AGENTS, CNS DEPRESSANTS GRUPPO LEPETIT S.P.A. (IT) 1977-08-09 US claimed