Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PDE2A | O00408 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460625 | 0.86 | KDM4E (0.56) | ALDH1A1KDM4EPDE2ACNR2JAK2 | |
| SCHEMBL24460661 | 0.86 | KDM4E (0.56) | ALDH1A1KDM4EPDE2ACNR2JAK2 | |
| SCHEMBL24460697 | 0.82 | PDE2A (0.52) | ALDH1A1KDM4EPDE2ACNR2DRD4 | |
| SCHEMBL24460749 | 0.82 | CNR2 (0.70) | ALDH1A1KDM4EPDE2ACNR2POLB | |
| SCHEMBL24460956 | 0.80 | CNR2 (0.53) | KDM4EPDE2ACNR2DRD4TMEM97 | |
| SCHEMBL24460730 | 0.80 | CNR2 (0.52) | ALDH1A1KDM4EPDE2ACNR2JAK2 | |
| SCHEMBL11403534 | 0.77 | CNR2 (0.60) | ALDH1A1KDM4ECNR2DRD4TEAD1 | |
| Hydrochloric Acid SCHEMBL11398713 | 0.76 | CNR2 (0.58) | ALDH1A1KDM4ECNR2DRD4TEAD1 | |
| SCHEMBL24460681 | 0.75 | KDM4E (0.62) | ALDH1A1KDM4EPDE2ACNR2POLB | |
| SCHEMBL30646793 | 0.74 | S1PR5 (0.41) | ALDH1A1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |