Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460625 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1CNR2PDE2AOPRL1 | |
| SCHEMBL24460624 | 0.89 | GAA (0.58) | KDM4EALDH1A1CNR2PDE2ALSS | |
| SCHEMBL24460749 | 0.88 | CNR2 (0.70) | KDM4EALDH1A1CNR2PDE2APOLB | |
| SCHEMBL24460628 | 0.86 | ALDH1A1 (0.52) | KDM4EALDH1A1CNR2PDE2APOLB | |
| SCHEMBL24460730 | 0.85 | CNR2 (0.52) | KDM4EALDH1A1CNR2PDE2APOLB | |
| SCHEMBL14642000 | 0.82 | MEN1 (0.61) | ALDH1A1CNR2LSSGAAMEN1 | |
| SCHEMBL6517324 | 0.82 | MEN1 (0.61) | ALDH1A1CNR2LSSGAAMEN1 | |
| SCHEMBL24460697 | 0.81 | PDE2A (0.52) | KDM4EALDH1A1CNR2PDE2A | |
| SCHEMBL24126796 | 0.80 | BCHE (0.63) | CNR2MEN1KMT2ABCHEACHE | |
| SCHEMBL24460681 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1CNR2PDE2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |