Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460625 | 0.85 | KDM4E (0.56) | CNR2KDM4EALDH1A1PDE2AKMT2A | |
| SCHEMBL24460661 | 0.85 | KDM4E (0.56) | CNR2KDM4EALDH1A1PDE2AKMT2A | |
| SCHEMBL24460749 | 0.84 | CNR2 (0.70) | CNR2KDM4EALDH1A1PDE2AKMT2A | |
| SCHEMBL24460628 | 0.80 | ALDH1A1 (0.52) | CNR2KDM4EALDH1A1PDE2APOLB | |
| SCHEMBL24460697 | 0.79 | PDE2A (0.52) | CNR2KDM4EALDH1A1PDE2ADRD4 | |
| SCHEMBL24460681 | 0.77 | KDM4E (0.62) | CNR2KDM4EALDH1A1PDE2APOLB | |
| SCHEMBL24126796 | 0.76 | BCHE (0.63) | CNR2KMT2AMEN1BCHEACHE | |
| SCHEMBL13059810 | 0.75 | ALDH1A1 (0.59) | KDM4EALDH1A1PDE2APOLBMAPT | |
| SCHEMBL24460624 | 0.73 | GAA (0.58) | CNR2KDM4EALDH1A1PDE2AKMT2A | |
| SCHEMBL24460758 | 0.72 | ALDH1A1 (0.59) | CNR2ALDH1A1PDE2ACCR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |